FT4 Rapid Quantitative Test (Chemiluminescence Immunoassay)

Application

Thyroxine (T4) is the main product secreted by the thyroid gland and an indispensable component of the hypothalamic-pituitary-thyroid regulatory system. Measurement of T4 levels can be used to diagnose hyperthyroidism, primary and secondary hypothyroidism, and to monitor the effects of TSH-inhibitory treatments.

Thyroid dysfunction can result in either an overproduction (hyperthyroidism) or underproduction (hypothyroidism) of T4 and its active form, T3. Additionally, dysfunction of the pituitary gland or hypothalamus can also affect thyroid function, as they exert direct control over thyroid hormone secretion via thyroid-stimulating hormone (TSH).

Generally, the concentration of free T4 (FT4) changes in parallel with the total T4 concentration. However, when total T4 levels fluctuate due to changes in thyroid-binding proteins, the measurement of FT4 becomes clinically significant, as it provides a more accurate assessment of the thyroid's functional state. Therefore, the determination of blood FT4 levels can be a useful tool in the auxiliary diagnosis of thyroid diseases and the assessment of treatment effectiveness in related patients.

Product Specification

Features

Smart - Photosensitive and Luminescent Microspheres

Rapid - Whole Blood Sample Type Supported & No Centrifuge Needed

Convenient - Room Temperature Storage & Minimal sample consumption

Clinical significance