HBP Rapid Quantitative Test (Chemiluminescence Immunoassay) is used for in vitro quantitative detection of the Heparin binding protein (HBP) concentration in human plasma that contains Sodium Citrate samples, mainly used for auxiliary diagnosis of inflammation diseases.
Application
Heparin-binding protein (HBP), also known as azurocidin or cationic antimicrobial protein of 37 kDa, is a mediator of inflammation and vascular permeability that is released from activated neutrophils. HBP has been shown to correlate with the development, severity, and prognosis of sepsis.
Recent studies have suggested that HBP may also be involved in the pathophysiology of acute kidney injury (AKI). This hypothesis is supported by data from a murine model as well as a human cell line study.
In two recent papers, plasma levels of HBP performed well in predicting the occurrence of septic AKI. The first study involved 296 patients with septic shock, and the second study included 59 patients with severe sepsis. These findings indicate that HBP may serve as a useful biomarker for the early detection and risk assessment of AKI in the context of sepsis.
Product Specification
|
Sample Volume |
Plasma: 10μL |
|
Test Time |
10 mins |
|
Measuring Range |
5.9-300 ng/mL |
|
Pack |
20T、40T、100T |
|
Storage |
2~30℃ |
Features
Smart - Photosensitive and Luminescent Microspheres
Rapid - Whole Blood Sample Type Supported & No Centrifuge Needed
Convenient - Room Temperature Storage & Minimal sample consumption
Clinical significance
Renal Function Assessment
Electrolyte Levels
Hormonal Assessments
Lipid Profile
Inflammatory Markers
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